Position Overview :

We are seeking a Technical Product Owner (TPO) with a strong background in Agile delivery, cloud engineering, and scientific computing to support Clinical Pharmacology and Pharmacometrics teams. This role requires a blend of technical depth, agile product management, and domain awareness in Clinical Pharmacology and regulatory data standards.

Key Responsibilities :

- Act as the primary liaison between business stakeholders, scientists, and technical teams, translating Clinical Pharmacology needs into technical requirements and product features.

- Define, prioritize, and manage the product backlog for HPC and scientific computing platforms.

- Lead Agile ceremonies including sprint planning, backlog grooming, daily scrums, sprint reviews, and retrospectives.

- Collaborate with cloud engineering, DevOps, and data teams to deliver scalable, secure, and compliant cloud-based solutions.

- Define and track product KPIs, ensuring continuous improvement in usability, performance, and compliance.

- Partner with R&D teams to support integration of pharmacology tools (Phoenix WinNonlin, Pirana, Monolix, MATLAB, NONMEM) with AWS HPC infrastructure.

- Collaborate with Quality and Compliance teams to ensure 21 CFR Part 11, GxP, and data integrity adherence.

- Work with data standardization and validation tools such as Pinnacle 21 for CDISC compliance.

- Manage Jira boards, workflows, and reporting for transparent delivery tracking and stakeholder communication.

- Facilitate cross-functional alignment with program managers, business analysts, and cloud architects.

- Support roadmap development and budget planning for product evolution.

Required Skills & Experience :

- Agile & Scrum: 5+ years as a Product Owner or Technical Product Manager in Agile/Scrum environments.

- Tools: Jira, Confluence, Azure DevOps (preferred), ServiceNow.

- Cloud & DevOps Exposure: AWS (EC2, S3, Batch, Lambda, CloudFormation) and CI/CD pipelines understanding.

- Domain Knowledge: Familiarity with Clinical Pharmacology, Pharmacometrics, and scientific data workflows.

- Regulatory Awareness: Working knowledge of CDISC standards (SDTM, ADaM) and data validation tools like Pinnacle 21.

- Hands-on experience with Pinnacle 21 Enterprise or Pinnacle 21 Community for validation of CDISC datasets.

- Ability to interpret Pinnacle 21 validation outputs and coordinate remediation with data management and programming teams.

Desirable Skills :

- Prior experience with scientific computing platforms, HPC workloads, or data governance solutions.

- Familiarity with data visualization and reporting tools (Spotfire, Tableau, Power BI).

- Exposure to Pirana, Phoenix WinNonlin, Monolix, or similar pharmacometric modeling tools.

Education :

- Bachelors or Masters degree in Computer Science, Bioinformatics, Life Sciences, or Biomedical Engineering.

- Certifications: Certified Scrum Product Owner (CSPO), AWS Cloud Practitioner, or SAFe PO/PM.